Pathomorphological features of calcinosis circumscripta in a dog

Pathomorphological features of calcinosis circumscripta in a dog

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Abstract A 19-month-old male German shepherd dog was presented with a hindlimb footpad mass.The HIGH DOSE R-LIPOIC ACID mass was excised and histopathology was performed.Grossly, the cut section of the mass had multiple wellcircumscribed nodules with a chalky appearance.Histopathologically, basophilic-stained calcium deposits of various sizes were distributed from dermis to subcutis, surrounded by epithelioid cells, multinucleated giant cells, and reactive Collections fibroblasts.

Myxoid metaplasia, calcium deposits in hair follicles, and psammomalike bodies were also found.These histopathologic observations will greatly help to understand the pathogenesis of calcinosis circumscripta.